Light Reduction in Prevention of Retinopathy of Prematurity (LIGHT-ROP)

A randomized, multicenter clinical trial in three centers that determined the efficacy of reduced ambient-light exposure to reduce the incidence of retinopathy of prematurity in 409 premature infants.

Sponsored by the National Eye Institute (NEI); 1995–2000 ($441,535).

Final Paper

Reynolds J, Hardy RJ, Kennedy KA, Spencer R, van Heuven WAJ, Fielder AR. Lack of efficacy of light reduction in preventing retinopathy of prematurity. N Engl J Med 1998;338:1572-1576.

All Papers