Hypertension Detection and Follow-up Program (HDFP)

A clinical trial in 14 centers which investigated the differences in mortality and selected morbidity between 10,940 patients randomly allocated to either an intensive hypertension control program or referral back to the regular medical care system.

Sponsored by the National Heart, Lung and Blood Institute (NHLBI); 1971–1993 ($18,059,234).

Final Paper

HDFP Cooperative Group. Five-year findings of the HDFP: I. Reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA 1979;242:2562- 2571.

Design Paper

Davis BR, Ford CE, Remington RD, Stamler R, Hawkins CM. HDFP design, methods, and baseline characteristics and blood pressure response of the study participants. Prog Cardiovasc Dis 1986;29:11-28.

All Papers